​What are Cannabinoids?

​Scientists have identified close to 500 phytochemicals in hemp plants. Hundreds of them are terpenoids.Terpenoids are the compounds that give fruits, flowers and herbs many of their desirable aromas, flavors and other special properties. Cannabinoids are a sub-class of terpenoids.
There are over 60 cannabinoids found in hemp and cannabis — the only place they are found. This is one of the many reasons hemp stands alone in the plant kingdom as a treasure chest of nutrition without equal.

WHAT IS CANNABINOID SYNERGY?

Each cannabinoid has its own individual properties, which is creating excitement in the scientific community. Besides terpenoids and cannabinoids, hemp contains many other vitamins, minerals, phytosterols, pigments, proteins, enzymes, essential sugars, polyphenol antioxidants, flavonoids and essential fatty acids.
While isolated cannabinoids have their own characteristic properties, the different compounds have synergistic effects when the whole symphony of phytonutrients are consumed together.
Synergy means that the combined effect is greater than the sum of the individual parts. Another way of thinking of this is 1+1. You know that 1+1 = 2. When hemp phytonutrients are consumed together, as they naturally occur in the plant, the nutritional benefits multiply, and it’s as if 1+1 now equals 3, or 4 or more!

​WHAT ARE SYNTHETIC CANNABINOIDS?
​
The unique health properties of hemp have been known to scientists for more than 50 years. Given that hemp is nutritional powerhouse, there have been  attempts by pharmaceutical companies to produce synthetic versions of isolated cannabinoid molecules.
As is common with synthetic chemicals, when cannabindiol is produced synthetically, the desired properties are reduced significantly, while undesirable side-effects appear.
​ What Is Hemp Oil?
​
CBD hemp oil is extracted from the stalks and seeds of industrial hemp plants. The plants used are specially bred to contain high concentrations of naturally occurring cannabidiol (CBD). Elixinol™ contains 18% CBD (slight seasonal variations may occur), which means that 10 ml or 10g (0.34 fl.oz) of Elixinol™ contains 1,800mg of CBD.

​Hemp Oil is NOT Psychoactive

You CANNOT get ‘high’ or intoxicated by consuming CBD hemp oil or any whole, raw natural product from industrial hemp plants. Unlike medical marijuana, hemp does not contain the psychoactive properties of THC. Additionally, scientific research* has documented that CBD is actually anti-psychoactive.

​Hemp Oil Extract Is In A Class 

All Its Own More than 400 phytonutrients exist in hemp plants. Our Super Critical Fluid Extraction technology allows us to extract all of these nutrients, without using any heat or harmful solvents. The result is a whole food with exceptional nutritional qualities plus the 400+ other nutrients in a naturally synergistic, easy-to-use, easy-to-absorb form. It truly is a one-of-a-kind product.

What Are Benefits of CBD Oil?
​
Cannabidiol (CBD) is the most predominant cannabinoid in hemp, and has many beneficial properties.
In its patent (#6,630,507) titled CANNABINOIDS AS ANTIOXIDANTS AND NEUROPROTECTANTS, the U.S. federal government makes many impressive claims about CBD, stating that:
  • “Cannabinoids are potent antioxidants… they easily penetrate tissues giving them the ability to enter the central nervous system and brain.”
  • “Non-psychoactive cannabinoids such as CBD are particularly advantageous as they are non-toxic… and exhibit unique antioxidant properties without the undesirable effects of THC.”
  • “The antioxidant strength of CBD is significantly greater than that of either Vitamin C or Vitamin E.”
Research on Safety CBD hemp oil is safe for the whole family, and more scientific studies are validating this all the time. Among the most prominent health care professionals who support the use of non-psychoactive CBD is physician and researcher William Courtney M.D.
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Why Does CBD Have So Many Potential Uses?

Why Does CBD Have So Many Potential Uses? Here at Elixinol, we have covered a wide range of potential therapeutic uses for cannabidiol (CBD), other cannabinoids and hemp oil. From epilepsy to PTSD, it can all sound too good to be true. So how could one plant have so many benefits?
Besides being the second most abundant cannabinoid in the Cannabis genus, and the most in hemp, CBD is now well-known for the sheer number of possible therapeutic uses1. Each use has different levels of evidence, from clinical trials where we see how effective it is in humans, to in vitro lab studies where we can see how it may work. The presence of endocannabinoid receptors in a range of tissues and organs help to explain CBD’s broad applications. However, it can also interact with other types of receptors in the body and brain.
The brain is made up of billions of highly specialised cells called neurons, along with several types of supporting cell2. Each neuron communicates with many other neurons by the synapses. Synapses are where two tiny bulbs on the ends of projections from the neuron cell come to meet. Neurons communicate with these by using chemicals known as neurotransmitters. Whether or not a neuron can “understand” the use of a certain neurotransmitter depends on if it has a receptor for that chemical. These receptors can respond to other chemicals too, such as the cannabinoids.
CBD, unlike THC, does not directly interact with the cannabinoid receptors, but instead works to increase the levels of our own cannabinoids. It also indirectly affects the signaling of these receptors. One of the non-cannabinoid receptors that CBD can influence is the dopamine receptors. Dopamine is involved with motivation and reward, as well as other cognitive and motor functions. This may be behind how CBD could help to fight cigarette cravings. In a study of 24 cigarette smokers, volunteers were given either an inhaler with CBD, or a placebo inhaler, and instructed to use it whenever they craved a cigarette3. The number of cigarettes smoked in the CBD group dropped significantly during the week, but not for the placebo group.
Animal studies have also shown that CBD can interact with some types of serotonin receptors, which may explain its effects on depression and anxiety. Its ability to interact with the serotonin 1A receptor may explain the documented effects of CBD on neuropathic pain, opioid dependence, and nausea and vomiting. There have been many anecdotal reports of hemp oil relieving nausea, even in severe vomiting caused by pharmaceuticals used for cancer. In addition, a study on shrews showed an effect of CBD on the serotonin 1A receptors which significantly reduced nausea and vomiting4. Its non-heated form, CBDA, had the same effect, but at a much lower dose.
Supporting the wide-ranging effects of CBD are the other cannabinoids, such as CBG and CBC, terpenes and other phytochemicals. These have shown anti-inflammatory, antidepressant, antioxidant and other effects. The number of potential benefits of hemp oil and CBD aren’t exactly “too good to be true”, but clinical trials are needed to confirm many of them.


References
1: https://www.leafly.com/news/science-tech/what-does-cbd-do
2: Tortora & Derrickson, 2012, Principles of Anatomy & Physiology, 12th edn, Wiley
3: http://www.ncbi.nlm.nih.gov/pubmed/23685330
4: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960260/
5: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165946/
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